Without symptoms like chest pain and others does not necessarily mean that there is no myocardial ischemia. But if the patient goes to the hospital to check, the inspection reveals the performance of myocardial ischemia is available. This kind of coronary heart disease patients suffer from is called silent myocardial ischemia, which is also known as hidden coronary artery disease. Even the pathophysiologic mechanism of silent myocardial ischemia has not been very clear, yet the primary cause of ischemic attack is the imbalance between myocardial oxygen supply and oxygen demand, which had been reached the consensus.

The observation results of the pathophysiological changing process of myocardial ischemia indicated that after the reduction of coronary blood flow, symptoms of angina are usually occurred following the ventricular dysfunction, hemodynamic abnormalities and ECG changes. Thus it can be speculated that patients with short-term and light degree myocardial ischemia can occur without symptoms of angina.

We often focus on physical- activity-induced silent myocardial ischemia, however the majority of silent myocardial ischemia usually occur during brain work rather than manual work. This fact prompted the activities of thinking can pass through the central nervous system and is likely to induce silent myocardial ischemia by the effects of catecholamines. In addition, the agitation of β-adrenergic receptor has also been considered as playing the mediate role in the continuing of ischemia inducement and ischemia caused by other mechanisms. Therefore, office workers who work in the office for a long time also need pay attention.

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